From Boston Take I-90 West / Mass Pike. Merge onto MA-9 West via exit number 12 towards Marlborough/Worcester. End at 333 Turnpike Road, Southborough, MA.

From Springfield Take I-291 North to I-90 E /Massachusetts Turnpike. Take exit number 11A onto I-495 North. Merge onto MA-9 E/Turnpike Road via exit number 23A. Make a U-Turn onto MA-9 W/Turnpike Road. End at 333 Turnpike Road, Southborough, MA.

From Providence, RI Take US-1 N to I-95 North. Follow I-95 North to I-495 North. Take exit number 23A onto MA-9 E/Turnpike Road. Make a U-Turn onto MA-9 W/Turnpike Road. End at 333 Turnpike Road, Southborough, MA.